The role of MRI in breast imaging
نویسنده
چکیده
Magnetic resonance imaging (MRI) of the breast is now recognized as an effective modality in evaluating specific groups of patients with breast lesions or breast cancer and patients suspected of having hereditary BRCA1/BRCA2 mutations. Sensitivity of MRI in detecting breast cancer is high (88%–100%) and exceeds that of mammography and ultrasonography in detecting lesions in patients with occult disease. The specific applications of breast MRI range from detecting tumors in women with breast implants to monitoring response to neoadjuvant chemotherapy. In addition, a growing number of institutions are offering MRI-guided biopsy. Still, breast MRI is not a substitute for routine screening mammography, and results need to be interpreted carefully in conjunction with mammography and ultrasonography. Controversies in Patient Management
منابع مشابه
Breast cancer imaging: a new role of Tc-99m sestamibi prone scintimammography for diagnosisof breast cancer
Mammography remians the procedure of choice in screening asymptomatic women for breast cancer. However, in patients with symptoms, other types of imaging play an important role in the detection of malignancies. The high cost and lack of availability of PET and MRI largely precludes the use in this patient population. TI-201 is nbt the imaging agent of choice because of its wash-out and redistri...
متن کاملIn vitro Study of SPIONs-C595 as Molecular Imaging Probe for Specific Breast Cancer (MCF-7) Cells Detection
Background: Magnetic resonance imaging (MRI) plays an essential role in molecular imaging by delivering the contrast agent into targeted cancer cells. The aim of this study was to evaluate the C595 monoclonal antibody-conjugated superparamagnetic iron oxide nanoparticles (SPIONs-C595) for the detection of breast cancer cell (MCF-7). Methods: The conjugation of monoclonal antibody and nanopartic...
متن کاملA Novel Biocompatible Nanoprobe Based on Lipoproteins for Breast Cancer Cell Imaging
Objective(s): Contrast-enhanced magnetic resonance imaging (MRI) of breast cancer provides valuable data on the disease state of patients. Biocompatible nanoprobes are expected to play a pivotal role in medical diagnosis in the future owing to their prominent advantages. The present study aimed to introduce a novel biocompatible nanoprobe based on lipoproteins for breast cancer cell imaging.<br...
متن کاملImaging features of estrogen-negative breast cancers: a correlation study with human epidermal growth factor type II overexpression
Background: Estrogen-negative breast cancers have different clinical course, prognostic features and treatment response in comparison to estrogen receptor-positive (ER-positive) breast cancers. Human epidermal growth factor receptor 2 (HER2) oncoprotein has found to have a pivotal role in natural cell growth and cell division and is suggested to be directly related to tumor invasiveness in brea...
متن کاملComparison between MRS and DWI in MRI of breast cancer
Introduction: Breast cancer is the most common cancer in women and is the second leading cause of cancer death (after lung cancer) in people throughout the world. Today, MRI is being used because of the limitations of x-ray mammography to detect breast cancer. Non-contrast sequences were associated to CE sequences in a breast MRI protocol for the sake of appraising morphologic ...
متن کاملGadolinium-Diethylenetriaminepenta-Acetic acid Conjugated with Monoclonal Antibody C595 as New Magnetic Resonance Imaging Contrast Agents for Breast Cancer (MCF-7) Detection
Background: The monoclonal antibody, C595, against breast cancer cell line was conjugated with cyclic anhydride gadolinium-diethylenetriaminepenta-acetic acid (Gd-cDTPAa) to produce Gd-DTPA-C595 and used as specific breast cancer cell line (MCF-7) contrast agents in magnetic resonance imaging (MRI). Methods: After incubation of breast cancer cell line (MCF-7), with different contrast agents (G...
متن کامل